Cell Disruption Made Easy


New Range Launched!

  • Reduced range
  • Various Flow rates availablee
  • ‘Budget’ system now available
  • Production system now available
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HFR System

  • Suitable for large volume processing
  • Various flow rates available
  • Protocols and results fully scalable with our existing models
  • Contact us to come and view our new model or to arrange a chance to try it with your own sample!
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Do you currently use a French Press?

Watch this video to see how you can achieve the same results on our Cell Disruptors, just quicker and more easily!

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Exceptional results at the push of a button

Achieve up to 98% cell lysis with S. cerevisiae from a single pass.

With a Constant Systems cell disruptor, you are guaranteed:

  • Consistency
  • Reproducibility
  • Reliability
  • Efficacy
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CSL In the Press

New research undertaken at our on-site laboratory has been published in the current issue of European Biopharmaceutical Review. Click here to view the article (taken from European Biopharmaceutical Review July 2016, pages 12-16. © Samedan Ltd.) and read about our work to replicate high pressure lysis results via alternative components at lower pressures in an attempt to reduce operational costs as well as energy consumption. Alternatively, click below to see the contents of the current issue of EBR.

More Information

Constant Systems Limited design, manufacture and distribute high pressure homogenisers capable of efficient lysis across a range of cell types, including expression systems such as E. coli and tough to break organisms such as yeasts, algae and Gram-positive bacteria. Our range of products offer a complete, scalable cell disruption solution from small research experiments to larger production operations and everything in between.

Our Cell Disruptors are highly utilised by research groups in the areas of drug discovery, protein characterisation and functional studies of cellular processes. To date, our systems have directly contributed to research published in over 1,200 peer reviewed papers across a range of academic journals, including Nature and the Journal of Biological Chemistry. Have a look at the list for yourself here, and see if there is scope for one of our machines to help you research your system of interest.