High Flow Rate Cell Disrupter

The HFR is the ideal production model and offers the same lysis efficiency as the standard CSL systems across the full range of processing pressures.

About High Flow Rate Cell Disrupter

The HFR is the ideal production model and offers the same lysis efficiency as the standard CSL systems across the full range of processing pressures yet can provide a vastly superior flow rate.

With lysis efficiencies of up to 95% or more and flow rates of up to 150 L/hr, this system can make short work of processing the entire contents of a production scale fermenter or bioreactor, even without prior pelleting and re-suspending.

The intuitive user interface offers complete control of the flow rate while the flow path accumulator ensures that the entire sample is processed smoothly and efficiently. This machine has been shown to give the same lysis results as the CF Range when processing tough to break cells types such as S. cerevisiae and N. oculata and the innovative heat exchange system ensures that the processed sample is completely chilled upon recovery when fitted with a circulating chiller.

 

 

 

 

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hfr-schematics

Specifications

  • Incorporates our unique disruption mechanism and precise hydraulic operating control system
  • Disruption pressure easily and accurately set and displayed digitally with a range of up to 40Kpsi as standard
  • Flow rate up to 150 L/hr at maximum pressure
  • Automatic shut down when process is complete
  • Various flow rates are available depending on desired maximum pressure
  • Pressure consistent and stable during the disruption cycle
  • Various configurations available for inlet and outlet, allowing direct connections to upstream and downstream equipment
  • Performance comparable to existing range of Constant Systems Ltd cell disruptors
  • Materials in contact with sample—316L and F51 duplex stainless steel or equivalent, EPDM
  • IQ/OQ available on request
  • Machine Dimensions – 1650 x 900 x 1250 (LxWxH)
  • Machine weight – 875 kg
  • Accumulator Dimension – 650 x 1700
  • Accumulator weight – 210 kg

Our Range

one-shot-cell-disrupter

One Shot Cell Disrupter

The OS Cell Disrupter is the smallest offering in the Constant Systems Cell Disruption range of products. At approximately 500mm² the OS sits very comfortable on the benchtop but is best suited when used on its tailor made trolley.

 

multi-shot-cell-disrupter

Multi Shot Cell Disrupter

Mutli Shot Cell Disrupter
The MC Cell Disrupter is the most versatile model for small volume processing offered by Constant Systems Limited. At approximately 500mm² the MC sits very comfortable on the benchtop but is best suited when used on its tailor made trolley.

continuous-flow-cell-disrupter

High Flow Rate Cell Disrupter

The CF Cell Disrupter offers Continuous Flow Processing with two models, the CF1 and CF2. Both models offer the same process and differ only by process speed, the CF1 offers up to 6L per hour and the CF2 offers up to 24L per hour processing rates.

 

Contact us now to find out more

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