“I manage a structural biology lab in the Rosalind Franklin Institute RFI. We have purchased two cell disruptors CF1. We have been using those for over 2 years now with no issues at all. And I have been using them in other institutes, as well as the team I manage, for several years, that they were adamant we should only have Constant Systems cell disruptors in our new building.
I have one of the cell disruptors with a cooling jacket for a 900ml volume, and another one with a smaller cup of 200ml, with a processing pump attached to it.
They were quite easy to use, once a training has been conducted to the users (primarily by the company, who dedicated a whole day of training to the users, including consumables and maintenance training for those who are interested).
We use in our lab’s mammalian, bacterial and yeast cells. We mainly process bacterial and yeast cells on the cell disruptors. The instructions given by the company were very clear and straight forward, in a way that every service the engineer finds minimal/traces of debris inside the machine.
They Constant Systems has a very nice, friendly, efficient, and highly knowledgeable team about their products. Whenever an issue is raised, their response is immediate and very useful. Never leave a client disappointed. “
Sheera Abdulla – Laboratory manager of the structural biology department in RFI.
Prof Ray Owens’ team at the RFI use the Constant System CF2 cell disruptor in their efforts to target kinase receptors with therapeutic agents. Imperative to isolating the high integrity transmembrane receptors was how the cell disruption process was carried out.