by constantsystems.com | 20 Mar, 2025
Abstract: Â This study investigates the impact of various cosolvents on the activity and stability of two dihydrofolate reductases (DHFRs): bacterial R67 DHFR and human DHFR (hDHFR). The research addresses a significant gap in understanding how cosolvents influence...
by constantsystems.com | 20 Mar, 2025
Abstract: This study investigates the role of the Scc4 protein in the loading of cohesin complexes onto chromosomes, focusing on the Escherichia coli system as a model organism. Cohesin is vital for maintaining genome integrity through its roles in sister chromatid...
by constantsystems.com | 20 Mar, 2025
Abstract: Horizontally acquired genes often integrate with ancestral gene regulatory systems to enhance bacterial adaptability and virulence. In this study, we report that the horizontally acquired regulatory gene ssrB activates the ancestral PhoP/PhoQ regulatory...
by constantsystems.com | 20 Mar, 2025
Abstract: Horizontally acquired genes often integrate with ancestral gene regulatory systems to enhance bacterial adaptability and virulence. In this study, we report that the horizontally acquired regulatory gene ssrB activates the ancestral PhoP/PhoQ regulatory...
